Which client is at greatest risk of developing osteoarthritis based on age and genetic predisposition?

The selection of the 65-year-old female with a family history as the client at greatest risk of developing osteoarthritis is based on two significant factors: age and genetic predisposition.

Osteoarthritis is primarily associated with aging, as the wear and tear on joints accumulate over time, leading to the degeneration of cartilage and changes in the bone structure. Individuals over 60, especially women, are at a notably higher risk for developing this condition due to factors such as hormonal changes and the natural aging process.

Additionally, genetic predisposition plays a crucial role in the development of osteoarthritis. A family history suggests that there may be hereditary factors or genetic markers that increase the likelihood of someone developing the disease. In this case, the combination of being 65 years old and having a family history aligns closely with the known risk factors for osteoarthritis, thereby placing this client at the highest risk compared to the others.

While factors like smoking and obesity can contribute to various health-related issues, including joint problems, they do not specifically correlate to the age and genetic predisposition as strongly as the chosen answer. The other options present factors that either do not weigh as heavily as age in relation to osteoarthritis risk or lack the element of family history, which is critical